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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccdc134Si:dkey-167k11.5. (229 aa)    
Predicted Functional Partners:
MEI1
Meiotic double-stranded break formation protein 1.
 
    
 0.737
LOC100708033
GTPase, IMAP family member 8.
    
 
 0.681
LOC100703489
GTPase, IMAP family member 8.
    
 
 0.681
LOC100706664
Amyloid beta precursor protein binding family A member 3.
      
 0.582
I3KVP0_ORENI
Ig-like domain-containing protein; Belongs to the MHC class I family.
      
 0.505
tmed2
Transmembrane p24 trafficking protein 2.
   
 
 0.493
zbtb20
Zinc finger and BTB domain containing 20.
    
 0.456
I3ITT5_ORENI
Exportin 1 (CRM1 homolog, yeast) a.
     
 0.436
LOC100703095
Exportin 1 (CRM1 homolog, yeast) b.
     
 0.436
mcrip1
MAPK regulated corepressor interacting protein 1.
      
 0.432
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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