Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
I3JP12_ORENICyclin I family, member 2; Belongs to the cyclin family. (423 aa)    
Predicted Functional Partners:
cdk5
Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.
    
 
 0.748
cdc6
Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family.
   
 0.740
cdc27
Cell division cycle 27.
   
 0.711
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.693
LOC100692625
Wee1-like protein kinase.
   
 0.673
pkmyt1
Protein kinase, membrane associated tyrosine/threonine 1.
   
 0.673
wee1
Wee1-like protein kinase.
   
 0.673
cdc20
Cell division cycle 20 homolog.
   
 0.669
FZR1
Fizzy/cell division cycle 20 related 1a.
   
 0.669
intu
Inturned planar cell polarity protein.
   
 0.669
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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