Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aff4AF4/FMR2 family, member 4. (1157 aa)    
Predicted Functional Partners:
cdk9
Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily.
    
 0.999
eaf1
ELL associated factor 1.
    
 0.999
eaf2
ELL associated factor 2.
    
 0.997
LOC100690070
Cyclin T1; Belongs to the cyclin family.
   
 0.992
LOC100709139
Cyclin T2b; Belongs to the cyclin family.
   
 0.989
LOC100698210
Cyclin T2; Belongs to the cyclin family.
   
 0.989
ell2
Elongation factor, RNA polymerase II, 2.
    
 0.987
LOC100694205
MLLT3 super elongation complex subunit.
    
 0.985
I3JUU4_ORENI
MLLT1 super elongation complex subunit a.
    
 0.985
Ell
Elongation factor RNA polymerase II.
    
 0.981
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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