Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tspan18Tetraspanin. (258 aa)    
Predicted Functional Partners:
tp53i11
Tumor protein p53 inducible protein 11b.
      
 0.672
LOC100703837
Metallophosphoesterase domain containing 2a.
      
 0.525
mpped1
Metallophosphoesterase domain containing 1.
      
 0.525
Prdm11
PR domain-containing protein 11.
     
 0.523
I3KPA0_ORENI
PHD finger protein 21Ab.
      
 0.504
txnl4a
Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.
      
 0.498
slc35f4
Solute carrier family 35 member F4.
      
 0.489
cd74
CD74 molecule, major histocompatibility complex, class II invariant chain a.
   
  
 0.472
rps14
Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.
   
  
 0.472
edar
Ectodysplasin A receptor.
      
 0.443
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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