Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
NR3C1Nuclear receptor subfamily 3 group C member 1. (843 aa)    
Predicted Functional Partners:
nrip1
Nuclear receptor interacting protein 1b.
  
 0.935
LOC100711482
Peptidylprolyl isomerase.
    
 0.932
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.918
nr3c2
Nuclear receptor subfamily 3, group C, member 2.
    
 0.916
LOC100534398
Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor).
     
  0.916
stip1
Stress-induced phosphoprotein 1.
    
 0.916
fkbp4
Peptidylprolyl isomerase.
    
 0.911
Hsp90ab1
Heat shock protein 90, alpha (cytosolic), class B member 1.
    
 0.910
LOC100701982
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.
    
 0.910
LOC100704884
Prostaglandin E synthase 3a (cytosolic).
   
 0.907
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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