Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLCO1C1Solute carrier organic anion transporter family member. (702 aa)    
Predicted Functional Partners:
LOC100707011
Solute carrier organic anion transporter family member.
     
  0.864
LOC100707278
Solute carrier organic anion transporter family member.
     
  0.857
SLC16A2
Solute carrier family 16 member 2.
   
 
 0.822
slc16a10
Solute carrier family 16 member 10.
   
 
 0.798
KCNA10
Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family.
      
 0.709
KCNA10-2
Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family.
      
 0.709
thap4
THAP domain containing 4.
      
 0.707
Dio2
Type II iodothyronine deiodinase.
      
 0.630
I3KXG6_ORENI
Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).
      
 0.629
pemt
Phosphatidylethanolamine N-methyltransferase; Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC); Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
   
  
 0.564
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (26%) [HD]