Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FGD6FYVE, RhoGEF and PH domain containing 6. (1250 aa)    
Predicted Functional Partners:
nr2c1
Nuclear receptor subfamily 2, group C, member 1.
      
 0.523
Uhmk1
U2AF homology motif (UHM) kinase 1.
      
 0.512
LOC100704732
Ras-related GTP binding A.
    
 
 0.498
Smdt1
Essential MCU regulator, mitochondrial.
    
 0.490
LOC100698144
Single-pass membrane protein with aspartate-rich tail 1b.
    
 0.490
MCUB
Mitochondrial calcium uniporter dominant negative beta subunit.
    
 0.485
mcu
Mitochondrial calcium uniporter.
    
 0.485
micu2
Mitochondrial calcium uptake 2.
   
 0.444
micu1
Mitochondrial calcium uptake 1.
   
 0.444
rptor
Regulatory associated protein of MTOR, complex 1.
    
 
 0.438
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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