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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3JPK2_ORENIUncharacterized protein. (632 aa)    
Predicted Functional Partners:
pdpk1
3-phosphoinositide dependent protein kinase 1b.
    
 0.763
rptor
Regulatory associated protein of MTOR, complex 1.
    
 0.757
smg1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
    
 0.747
mtor
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.747
Rictor
RPTOR independent companion of MTOR, complex 2 a.
    
 0.713
rps6
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
    
 0.701
mapkap1
MAPK associated protein 1.
    
 0.697
tsc2
Rap-GAP domain-containing protein.
    
 0.600
mlst8
MTOR associated protein, LST8 homolog (S. cerevisiae).
    
 0.570
atp5pb
ATP synthase peripheral stalk-membrane subunit b.
   
 
 0.548
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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