Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100705410Calcium/calmodulin-dependent protein kinase 1Db; Belongs to the protein kinase superfamily. (412 aa)    
Predicted Functional Partners:
calml4
Calmodulin-like 4a.
    
 0.928
LOC100701793
Calmodulin-like 4b.
    
 0.911
ENSONIP00000045107
annotation not available
    
 0.873
ENSONIP00000050053
annotation not available
    
 0.873
calm1
Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family.
    
 0.873
dcx
Doublecortin.
 
  
 
 0.856
ENSONIP00000032100
Calmodulin 2a (phosphorylase kinase, delta).
    
 0.739
atf4
Activating transcription factor 4a.
   
  0.660
nos1
Nitric oxide synthase; Produces nitric oxide (NO).
   
 0.634
creb5
cAMP responsive element binding protein 5b.
     
 0.616
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.