I3JPT9_ORENI protein (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

I3JPT9_ORENI

Sp9 transcription factor. (428 aa)

Predicted Functional Partners:

wnt2b

0.498

LOC100711913

0.492

fndc3a

0.484

ext2

0.482

I3J6X6_ORENI

0.481

extl3

0.478

shh

0.464

LOC100698703

0.448

rspo2

0.445

dlx6

0.428

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3J6X6_ORENI	I3JPT9_ORENI	ENSONIP00000004616	ENSONIP00000010883	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Sp9 transcription factor.	0.481
I3J6X6_ORENI	LOC100698703	ENSONIP00000004616	ENSONIP00000028267	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	T-box transcription factor 5a.	0.504
I3J6X6_ORENI	LOC100711913	ENSONIP00000004616	ENSONIP00000001559	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.503
I3J6X6_ORENI	dlx6	ENSONIP00000004616	ENSONIP00000033263	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Distal-less homeobox 6a.	0.470
I3J6X6_ORENI	ext2	ENSONIP00000004616	ENSONIP00000032033	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	0.496
I3J6X6_ORENI	extl3	ENSONIP00000004616	ENSONIP00000007416	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Exostosin-like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.	0.493
I3J6X6_ORENI	fndc3a	ENSONIP00000004616	ENSONIP00000078036	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibronectin type III domain containing 3A.	0.501
I3J6X6_ORENI	rspo2	ENSONIP00000004616	ENSONIP00000000055	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	R-spondin 2.	0.431
I3J6X6_ORENI	shh	ENSONIP00000004616	ENSONIP00000007484	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.470
I3J6X6_ORENI	wnt2b	ENSONIP00000004616	ENSONIP00000014493	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.472
I3JPT9_ORENI	I3J6X6_ORENI	ENSONIP00000010883	ENSONIP00000004616	Sp9 transcription factor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.481
I3JPT9_ORENI	LOC100698703	ENSONIP00000010883	ENSONIP00000028267	Sp9 transcription factor.	T-box transcription factor 5a.	0.448
I3JPT9_ORENI	LOC100711913	ENSONIP00000010883	ENSONIP00000001559	Sp9 transcription factor.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.492
I3JPT9_ORENI	dlx6	ENSONIP00000010883	ENSONIP00000033263	Sp9 transcription factor.	Distal-less homeobox 6a.	0.428
I3JPT9_ORENI	ext2	ENSONIP00000010883	ENSONIP00000032033	Sp9 transcription factor.	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	0.482
I3JPT9_ORENI	extl3	ENSONIP00000010883	ENSONIP00000007416	Sp9 transcription factor.	Exostosin-like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.	0.478
I3JPT9_ORENI	fndc3a	ENSONIP00000010883	ENSONIP00000078036	Sp9 transcription factor.	Fibronectin type III domain containing 3A.	0.484
I3JPT9_ORENI	rspo2	ENSONIP00000010883	ENSONIP00000000055	Sp9 transcription factor.	R-spondin 2.	0.445
I3JPT9_ORENI	shh	ENSONIP00000010883	ENSONIP00000007484	Sp9 transcription factor.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.464
I3JPT9_ORENI	wnt2b	ENSONIP00000010883	ENSONIP00000014493	Sp9 transcription factor.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.498