Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100702791Nuclear receptor subfamily 1, group D, member 2a. (599 aa)    
Predicted Functional Partners:
I3JS28_ORENI
Nuclear receptor subfamily 1, group d, member 1.
   
 0.877
LOC100691220
Neuronal PAS domain protein 2.
    
 0.823
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.805
arntl
Aryl hydrocarbon receptor nuclear translocator-like 1a.
    
 0.777
ncor2
Nuclear receptor corepressor 2.
    
 0.775
ncor1
Nuclear receptor corepressor 1.
    
 0.775
LOC100707270
Nuclear factor, interleukin 3 regulated, member 6.
   
 0.771
I3JJ43_ORENI
D site albumin promoter binding protein a.
   
 0.762
LOC100698155
D site albumin promoter binding protein b.
   
 0.762
nr1h3
Nuclear receptor subfamily 1, group H, member 3.
   
 0.749
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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