Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100698940Crystallin, beta A1b; Belongs to the beta/gamma-crystallin family. (196 aa)    
Predicted Functional Partners:
LOC100703162
Crystallin, beta B2; Belongs to the beta/gamma-crystallin family.
   
   0.554
I3KXW1_ORENI
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
  
  
 0.526
LOC100701181
Microtubule-associated protein 1 light chain 3 gamma, like.
      
 0.493
LOC100706349
Major intrinsic protein of lens fiber b; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
  
 0.489
bfsp2
Beaded filament structural protein 2, phakinin; Belongs to the intermediate filament family.
   
  
 0.459
LOC102076973
Sal-like protein 2 isoform X1.
   
  
 0.427
Sall2
Sal-like protein 2.
   
  
 0.427
six3
SIX homeobox 3a.
   
  
 0.424
LOC100697477
Neurexophilin; May be signaling molecules that resemble neuropeptides.
  
    0.423
BFSP1
Beaded filament structural protein 1; Belongs to the intermediate filament family.
   
  
 0.422
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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