Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDZRN4PDZ domain containing ring finger 4. (763 aa)    
Predicted Functional Partners:
ENSONIP00000038349
RING finger protein 223.
    
 0.768
mib2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.760
ripk4
Receptor-interacting serine-threonine kinase 4.
   
 0.656
Birc6
Baculoviral IAP repeat containing 6.
   
 0.626
LOC102081483
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.602
Ecsit
ECSIT signalling integrator.
    
 0.591
ankrd22
Ankyrin repeat domain 22.
    
 0.591
det1
DET1 partner of COP1 E3 ubiquitin ligase.
    
 0.565
rps27a
Ribosomal protein S27a.
    
 0.550
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.544
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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