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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
usp48Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family. (1050 aa)    
Predicted Functional Partners:
trip12
Thyroid hormone receptor interactor 12.
   
 
 0.860
rps27a
Ribosomal protein S27a.
   
 0.806
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
 0.803
Ubl7
Ubiquitin-like 7b (bone marrow stromal cell-derived).
   
 0.694
usp5
Ubiquitin carboxyl-terminal hydrolase.
   
 
 0.686
usp13
Ubiquitinyl hydrolase 1.
   
 
 0.686
usp30
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.685
LOC100691476
Ubiquitin-like protein 4A.
   
 0.681
uvssa
UV-stimulated scaffold protein A.
    
 0.662
traf2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.660
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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