Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3JQ01_ORENIYY1 associated factor 2. (51 aa)    
Predicted Functional Partners:
I3KQY8_ORENI
Si:ch211-195d17.2.
   
 0.937
Pcgf5
Polycomb group ring finger 5a.
    
 0.935
pcgf1
Polycomb group ring finger 1.
    
 0.924
PCGF3
Polycomb group ring finger 3.
    
 0.916
pcgf6
Polycomb group RING finger protein 6.
    
 0.905
RING1
RING-type domain-containing protein.
    
 0.903
rnf2
Ring finger protein 2.
    
 0.903
wdr5
WD repeat domain 5.
    
 
 0.871
Bmi1
Bmi1 polycomb ring finger oncogene 1a.
    
 0.862
pcgf2
RING-type domain-containing protein.
    
 0.861
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (28%) [HD]