Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
abhd11Abhydrolase domain containing 11. (335 aa)    
Predicted Functional Partners:
rogdi
Rogdi atypical leucine zipper.
      
 0.768
farsa
Phenylalanyl-tRNA synthetase subunit alpha.
     
 0.702
abhd18
Abhydrolase domain containing 18.
      
 0.697
abhd6
Abhydrolase domain containing 6.
      
 0.641
LOC100711605
Malate synthase-like.
    
 0.640
akr7a2
Aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase).
   
 
 0.637
farsb
Phenylalanyl-tRNA synthetase subunit beta.
  
  
 0.637
ND1
NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family.
      
 0.619
rcc1l
RCC1 like.
   
  
 0.615
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
 
      0.609
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (14%) [HD]