Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Dock7Dedicator of cytokinesis 7; Belongs to the DOCK family. (2142 aa)    
Predicted Functional Partners:
cdc42
Cell division cycle 42.
   
 0.787
rhoh
Ras homolog family member H.
   
 0.690
rhoq
Ras homolog family member Q.
   
 0.690
grb2
Growth factor receptor-bound protein 2b.
   
 0.614
Arpc3
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
 
 0.610
ENSONIP00000047028
Actin related protein 2/3 complex, subunit 3.
    
 
 0.610
raver2
Ribonucleoprotein PTB-binding 2 isoform X2.
      
 0.600
LOC100711408
Myosin VIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.587
I3KR57_ORENI
Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.587
LOC100705444
Uncharacterized protein.
   
 0.586
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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