STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (184 aa)    
Predicted Functional Partners:
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
    
 0.982
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.978
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.978
ccna2
Cyclin A2; Belongs to the cyclin family.
    
 0.977
ccna1
Cyclin A1; Belongs to the cyclin family.
    
 0.977
LOC100692568
Cyclin E2; Belongs to the cyclin family.
   
 0.976
Ccne1
Cyclin E1; Belongs to the cyclin family.
   
 0.976
LOC102075526
Cyclin E2; Belongs to the cyclin family.
   
 0.976
ENSONIP00000000047
RAC-gamma serine/threonine-protein kinase.
    
 0.952
LOC100707971
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.952
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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