Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
I3JQH3_ORENILow density lipoprotein receptor-related protein 8, apolipoprotein e receptor. (949 aa)    
Predicted Functional Partners:
RELN
Reelin.
    
 0.958
pcsk9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
    
 0.897
mylip
Myosin regulatory light chain interacting protein a.
    
 0.874
ldlrap1
Low density lipoprotein receptor adaptor protein 1b.
    
 0.841
faf1
Fas (TNFRSF6) associated factor 1.
      
 0.838
LOC100693720
DAB adaptor protein 1b.
    
 0.829
I3J3Q9_ORENI
DAB adaptor protein 1a.
    
 0.829
LOC100699941
Putative apolipoprotein E.
    
 0.777
Lrpap1
Low density lipoprotein receptor-related protein associated protein 1.
    
 0.758
fbxl6
F-box domain-containing protein.
   
  
 0.756
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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