Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
stk39Serine threonine kinase 39. (505 aa)    
Predicted Functional Partners:
sec61g
SEC61 translocon gamma subunit.
   
 
 0.813
sec62
SEC62 homolog, preprotein translocation factor.
    
 
 0.811
WNK3
WNK lysine deficient protein kinase 2.
    
0.773
slc12a3
Solute carrier family 12 member 3.
    
 0.739
slc12a1
Solute carrier family 12 member 1.
    
 0.739
LOC100704048
Solute carrier family 12 member 2.
    
 0.739
LOC100694941
Uncharacterized protein.
    
 0.739
sec63
SEC63 homolog, protein translocation regulator.
    
 
 0.735
wnk4
Serine/threonine-protein kinase WNK4 isoform X1.
    
 0.724
LOC102079935
WNK lysine deficient protein kinase 1a.
    
 0.724
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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