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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
I3JQL3_ORENIFork-head domain-containing protein. (533 aa)    
Predicted Functional Partners:
cbfb
Core-binding factor subunit beta.
    
 0.552
nfatc2
Nuclear factor of activated T cells 2a.
    
 0.462
I3IYW8_ORENI
Runt domain-containing protein.
    
 0.456
LOC100691239
Runt-related transcription factor.
    
 0.456
runx3
Runt-related transcription factor.
    
 0.456
runx2
Runt-related transcription factor.
    
 0.456
wdr5
WD repeat domain 5.
      
 0.422
LOC100706011
POU domain protein.
    
 0.415
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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