| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC100711459 | bmt2 | ENSONIP00000000944 | ENSONIP00000011161 | Glycogenin 1a. | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | 0.574 |
| LOC100711459 | gys1 | ENSONIP00000000944 | ENSONIP00000056500 | Glycogenin 1a. | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. | 0.993 |
| LOC100711459 | gys2 | ENSONIP00000000944 | ENSONIP00000040518 | Glycogenin 1a. | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. | 0.993 |
| Nprl3 | SZT2 | ENSONIP00000077046 | ENSONIP00000009160 | NPR3-like, GATOR1 complex subunit. | SZT2 subunit of KICSTOR complex. | 0.980 |
| Nprl3 | bmt2 | ENSONIP00000077046 | ENSONIP00000011161 | NPR3-like, GATOR1 complex subunit. | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | 0.659 |
| Nprl3 | depdc5 | ENSONIP00000077046 | ENSONIP00000066237 | NPR3-like, GATOR1 complex subunit. | DEP domain containing 5. | 0.999 |
| Nprl3 | itfg2 | ENSONIP00000077046 | ENSONIP00000072695 | NPR3-like, GATOR1 complex subunit. | Integrin alpha FG-GAP repeat containing 2. | 0.803 |
| Nprl3 | kptn | ENSONIP00000077046 | ENSONIP00000050959 | NPR3-like, GATOR1 complex subunit. | Kaptin (actin binding protein). | 0.988 |
| Nprl3 | lg17h12orf66 | ENSONIP00000077046 | ENSONIP00000022659 | NPR3-like, GATOR1 complex subunit. | Si:ch211-125a15.1. | 0.831 |
| Nprl3 | nprl2 | ENSONIP00000077046 | ENSONIP00000004997 | NPR3-like, GATOR1 complex subunit. | NPR2 like, GATOR1 complex subunit. | 0.999 |
| SZT2 | Nprl3 | ENSONIP00000009160 | ENSONIP00000077046 | SZT2 subunit of KICSTOR complex. | NPR3-like, GATOR1 complex subunit. | 0.980 |
| SZT2 | bmt2 | ENSONIP00000009160 | ENSONIP00000011161 | SZT2 subunit of KICSTOR complex. | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | 0.674 |
| SZT2 | depdc5 | ENSONIP00000009160 | ENSONIP00000066237 | SZT2 subunit of KICSTOR complex. | DEP domain containing 5. | 0.983 |
| SZT2 | itfg2 | ENSONIP00000009160 | ENSONIP00000072695 | SZT2 subunit of KICSTOR complex. | Integrin alpha FG-GAP repeat containing 2. | 0.991 |
| SZT2 | kptn | ENSONIP00000009160 | ENSONIP00000050959 | SZT2 subunit of KICSTOR complex. | Kaptin (actin binding protein). | 0.992 |
| SZT2 | lg17h12orf66 | ENSONIP00000009160 | ENSONIP00000022659 | SZT2 subunit of KICSTOR complex. | Si:ch211-125a15.1. | 0.991 |
| SZT2 | nprl2 | ENSONIP00000009160 | ENSONIP00000004997 | SZT2 subunit of KICSTOR complex. | NPR2 like, GATOR1 complex subunit. | 0.978 |
| bmt2 | LOC100711459 | ENSONIP00000011161 | ENSONIP00000000944 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | Glycogenin 1a. | 0.574 |
| bmt2 | Nprl3 | ENSONIP00000011161 | ENSONIP00000077046 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | NPR3-like, GATOR1 complex subunit. | 0.659 |
| bmt2 | SZT2 | ENSONIP00000011161 | ENSONIP00000009160 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] | SZT2 subunit of KICSTOR complex. | 0.674 |