Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC100709626Wolfram syndrome 1a (wolframin). (1062 aa)    
Predicted Functional Partners:
atf6
Activating transcription factor 6.
    
 0.901
LOC100705378
BZIP domain-containing protein.
    
 0.901
Adgrv1
Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.
      
 0.654
rpgrip1l
RPGRIP1 like.
      
 0.654
stox1
Storkhead box 1.
      
 0.654
elf2
E74-like factor 2b (ets domain transcription factor).
      
 0.631
Xbp1
X-box binding protein 1.
    
 0.628
LOC100690299
RIC8 guanine nucleotide exchange factor A.
   
    0.615
slc26a5
Solute carrier family 26 member 5.
   
  
 0.580
opa3
Outer mitochondrial membrane lipid metabolism regulator OPA3.
      
 0.574
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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