Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC100695238Si:ch211-262h13.5. (407 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.652
LOC100702671
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.617
LOC100702940
Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily.
   
 0.617
LOC100692670
Ras-related GTP binding D.
      
 0.550
LOC100702432
Uncharacterized protein.
   
 
 0.494
I3J168_ORENI
Zinc finger, FYVE domain containing 9b.
      
 0.483
LOC100694811
Hemopexin a.
   
 
 0.481
LOC100692890
RAN binding protein 2.
    
 0.470
itih2
Inter-alpha-trypsin inhibitor heavy chain 2.
      
 0.456
SPOCK2
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2.
      
 0.454
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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