STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100710690Histone PARylation factor 1. (352 aa)    
Predicted Functional Partners:
Parp2
Poly [ADP-ribose] polymerase.
    
 
 0.932
parp1
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 
 0.903
parp3
Poly [ADP-ribose] polymerase.
    
 
 0.788
vwa5b2
Von Willebrand factor A domain containing 5B2.
    
 
 0.618
parp4
Poly [ADP-ribose] polymerase.
    
 
 0.618
Cwc22
MI domain-containing protein.
      
 0.574
larp7
La ribonucleoprotein domain family, member 7.
   
  
 0.478
LOC100702930
Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.
    
 
 0.464
LOC100699679
H2A histone family, member Y; Belongs to the histone H2A family.
    
 
 0.464
exosc8
Exosome component 8.
      
 0.456
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.