Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cd247T-cell surface glycoprotein CD3 zeta chain. (150 aa)    
Predicted Functional Partners:
cd3e
T-cell surface glycoprotein CD3 epsilon chain.
   
 0.999
I3KIS7_ORENI
Uncharacterized protein.
   
 0.999
LOC100696446
Tyrosine-protein kinase.
   
 0.989
syk
Tyrosine-protein kinase.
   
 0.986
I3KX32_ORENI
Ig-like domain-containing protein.
   
 
 0.980
LOC102079789
Fibronectin type-III domain-containing protein.
   
  
 0.904
ENSONIP00000055480
annotation not available
   
 
  0.895
LOC102076862
Ig-like domain-containing protein.
   
 
 0.872
cd2
Uncharacterized protein.
   
 
 0.872
LOC100700918
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 0.854
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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