Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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LOC100705805Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1105 aa)    
Predicted Functional Partners:
LOC100699977
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
 0.896
pde3b
Phosphodiesterase.
   
 0.864
LOC100703527
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
   
 0.849
I3J8H8_ORENI
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
   
 0.849
LOC100711715
Rap guanine nucleotide exchange factor (GEF) 3.
   
 
 0.849
LOC100695013
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.
   
 0.849
LOC100702054
Guanine nucleotide binding protein (G protein), beta 5b.
    
 0.848
gng3
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.842
I3JFY9_ORENI
Phosphodiesterase.
   
 0.840
LOC100710868
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A isoform X4.
   
 0.840
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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