Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
I3JR68_ORENINME/NM23 family member 8; Belongs to the NDK family. (641 aa)    
Predicted Functional Partners:
ENSONIP00000016918
Adenylate kinase 9.
  
 0.961
wdr90
WD repeat domain 90.
   
 0.933
ENSONIP00000056453
annotation not available
   
 
 0.933
LOC100707731
Radial spoke head component 4A.
   
 
 0.927
mrps11
Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family.
  
 0.924
dnai1
Dynein, axonemal, intermediate chain 1, paralog 2.
   
 
 0.923
efhb
Uncharacterized protein.
   
   0.917
trim23
Tripartite motif containing 23.
   
 0.914
prdx5
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.913
dnai2
Dynein, axonemal, intermediate chain 2b.
   
 
 0.913
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (26%) [HD]