Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
marchf4Membrane-associated ring finger (C3HC4) 4. (400 aa)    
Predicted Functional Partners:
tmem106c
Transmembrane protein 106C.
      
 0.717
ENSONIP00000076186
Ribosomal RNA processing 15 homolog.
      
 0.694
ube2ql1
Ubiquitin-conjugating enzyme E2Q family-like 1.
      
 0.661
gpatch2
G-patch domain-containing protein.
      
 0.654
ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1.
      
 0.620
Spata17
Uncharacterized protein.
      
 0.576
ube2g2
Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.564
haus1
HAUS augmin-like complex, subunit 1.
      
 0.521
LOC100706438
Sulfotransferase; Belongs to the sulfotransferase 1 family.
     
 0.506
C11orf96
Uncharacterized protein C11orf96 homolog.
      
 0.493
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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