Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmem53Transmembrane protein 53. (286 aa)    
Predicted Functional Partners:
ogfod3
Urotensin-2 receptor 2.
      
 0.923
pigb
Mannosyltransferase.
      
 0.922
zdhhc6
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.919
smad1
Mothers against decapentaplegic homolog.
     
  0.916
I3K002_ORENI
Uncharacterized protein.
     
  0.916
smad9
Mothers against decapentaplegic homolog.
     
  0.916
LOC100703688
Uncharacterized protein.
     
  0.916
LOC100706145
Mothers against decapentaplegic homolog.
     
  0.916
ndc1
NDC1 transmembrane nucleoporin.
      
 0.914
tmem209
Transmembrane protein 209.
      
 0.906
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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