Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
map3k13Mitogen-activated protein kinase kinase kinase. (1015 aa)    
Predicted Functional Partners:
I3KP91_ORENI
Mitogen-activated protein kinase kinase 7.
    
 0.951
I3KK13_ORENI
Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.
     
  0.916
map3k12
Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.
     
  0.916
Mycbp2
MYC binding protein 2.
    
 0.914
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 
 0.749
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
     
 0.610
ZNF516
Zinc finger protein 516.
      
 0.476
fgf6
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.463
LOC100708453
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.463
FGF13
Fibroblast growth factor 13 isoform X5.
      
 0.456
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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