Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC100692632Keratin 18a, tandem duplicate 1; Belongs to the intermediate filament family. (451 aa)    
Predicted Functional Partners:
I3JRJ3_ORENI
Keratin 5; Belongs to the intermediate filament family.
   
 0.710
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.691
LOC100702817
Keratin 8; Belongs to the intermediate filament family.
   
 0.582
cpsf1
Cleavage and polyadenylation specific factor 1.
    
  0.526
ino80e
INO80 complex subunit E.
   
 0.521
cpsf4
Cleavage and polyadenylation specific factor 4.
    
 0.475
LOC100692890
RAN binding protein 2.
    
 0.470
twf2
WD repeat domain 82.
    
 0.463
LOC100709494
Twinfilin actin-binding protein 2b.
    
 0.463
LOC100702519
Zgc:158846; Belongs to the intermediate filament family.
   
  0.450
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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