STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC100702817Keratin 8; Belongs to the intermediate filament family. (520 aa)    
Predicted Functional Partners:
I3JRJ3_ORENI
Keratin 5; Belongs to the intermediate filament family.
   
  0.924
LOC102081358
Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 
 0.919
I3JL62_ORENI
Uncharacterized protein.
   
 
 0.814
I3JLS7_ORENI
Si:ch73-74h11.1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 
 0.814
LOC100711808
Talin 1.
    
 
 0.814
ENSONIP00000065416
Desmoglein 2.
   
 
 0.814
ireb2
Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.
   
 
 0.727
rps6
40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.
      
 0.721
ino80e
INO80 complex subunit E.
   
  0.718
tmlhe
Trimethyllysine hydroxylase, epsilon.
    
 
 0.689
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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