Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
atp13a2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1158 aa)    
Predicted Functional Partners:
pink1
PTEN induced kinase 1.
      
 0.873
park7
Parkinson protein 7.
     
 0.855
LOC100691213
Uncharacterized protein; Belongs to the synuclein family.
   
  
 0.763
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.762
tmem175
Transmembrane protein 175.
      
 0.754
spg11
SPG11 vesicle trafficking associated, spatacsin.
      
 0.753
I3KAX8_ORENI
Ataxin 2.
   
  
 0.753
fbxo7
F-box protein 7.
   
  
 0.752
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
   
  
 0.743
RIC3
Protein RIC-3.
      
 0.725
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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