Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ShbgLAM_G_DOMAIN domain-containing protein. (398 aa)    
Predicted Functional Partners:
amh
Anti-mullerian hormone.
      
 0.638
I3KMU3_ORENI
Insulin-like growth factor 1.
      
 0.607
gnrh1
Uncharacterized protein.
      
 0.523
LOC100534522
Prolactin.
      
 0.508
LOC100697904
Prolactin 2.
      
 0.508
TMEM236
Transmembrane protein 236.
    
   0.497
LOC100707859
Transmembrane protein 236.
    
   0.497
LOC106098551
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
      
 0.459
syt1
Synaptotagmin Ia.
   
  
 0.458
LOC100710649
Synaptotagmin Ib.
   
  
 0.458
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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