Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dthd1Death domain containing 1. (898 aa)    
Predicted Functional Partners:
RS1
Retinoschisin 1.
      
 0.700
cluap1
Clusterin associated protein 1.
      
 0.656
morn5
MORN repeat containing 5.
      
 0.611
CDHR1
Cadherin related family member 1.
      
 0.537
LOC100690479
Cadherin-related family member 1a.
      
 0.537
LOC100701258
Uncharacterized protein.
      
 0.522
cfap161
Cilia- and flagella-associated protein 161.
      
 0.521
Rd3
Retinal degeneration 3, GUCY2D regulator.
      
 0.518
cct2
T-complex protein 1 subunit beta.
      
 0.489
ift140
Intraflagellar transport 140 homolog (Chlamydomonas).
      
 0.486
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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