Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
arap2Uncharacterized protein. (1680 aa)    
Predicted Functional Partners:
rap1b
Uncharacterized protein.
     
 0.621
LOC100690250
Ras-related protein Rap-1A.
     
 0.621
grb2
Growth factor receptor-bound protein 2b.
    
 
 0.615
cdc42
Cell division cycle 42.
   
 0.550
LOC100691828
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3.
   
 0.511
LOC100697412
Tyrosine-protein kinase.
   
  0.474
LOC100693162
Tyrosine-protein kinase.
   
  0.474
LOC100693436
Protein-tyrosine kinase 6 isoform X1.
   
  0.474
fyn
Tyrosine-protein kinase.
   
  0.474
I3KIA3_ORENI
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.
     
 0.469
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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