LOC100697135 protein (Oreochromis niloticus)

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LOC100697135

NDK domain-containing protein; Belongs to the NDK family. (239 aa)

Predicted Functional Partners:

LOC100703020

0.962

mrps22

0.948

ENSONIP00000016918

0.947

ak3

0.943

mrps16

0.941

itpa

0.940

nme6

0.935

dtymk

0.934

cmpk1

0.934

hddc3

0.931

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000016918	LOC100697135	ENSONIP00000016918	ENSONIP00000011679	Adenylate kinase 9.	NDK domain-containing protein; Belongs to the NDK family.	0.947
ENSONIP00000016918	LOC100703020	ENSONIP00000016918	ENSONIP00000024381	Adenylate kinase 9.	Nucleoside diphosphate kinase.	0.947
ENSONIP00000016918	ak3	ENSONIP00000016918	ENSONIP00000052218	Adenylate kinase 9.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.975
ENSONIP00000016918	cmpk1	ENSONIP00000016918	ENSONIP00000074525	Adenylate kinase 9.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.942
ENSONIP00000016918	dtymk	ENSONIP00000016918	ENSONIP00000024266	Adenylate kinase 9.	Deoxythymidylate kinase (thymidylate kinase).	0.959
ENSONIP00000016918	hddc3	ENSONIP00000016918	ENSONIP00000008804	Adenylate kinase 9.	HD domain containing 3.	0.926
ENSONIP00000016918	itpa	ENSONIP00000016918	ENSONIP00000068672	Adenylate kinase 9.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.952
ENSONIP00000016918	nme6	ENSONIP00000016918	ENSONIP00000068813	Adenylate kinase 9.	Nucleoside diphosphate kinase 6 isoform X1.	0.947
LOC100697135	ENSONIP00000016918	ENSONIP00000011679	ENSONIP00000016918	NDK domain-containing protein; Belongs to the NDK family.	Adenylate kinase 9.	0.947
LOC100697135	LOC100703020	ENSONIP00000011679	ENSONIP00000024381	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.962
LOC100697135	ak3	ENSONIP00000011679	ENSONIP00000052218	NDK domain-containing protein; Belongs to the NDK family.	GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.	0.943
LOC100697135	cmpk1	ENSONIP00000011679	ENSONIP00000074525	NDK domain-containing protein; Belongs to the NDK family.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.934
LOC100697135	dtymk	ENSONIP00000011679	ENSONIP00000024266	NDK domain-containing protein; Belongs to the NDK family.	Deoxythymidylate kinase (thymidylate kinase).	0.934
LOC100697135	hddc3	ENSONIP00000011679	ENSONIP00000008804	NDK domain-containing protein; Belongs to the NDK family.	HD domain containing 3.	0.931
LOC100697135	itpa	ENSONIP00000011679	ENSONIP00000068672	NDK domain-containing protein; Belongs to the NDK family.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.940
LOC100697135	mrps16	ENSONIP00000011679	ENSONIP00000017954	NDK domain-containing protein; Belongs to the NDK family.	Mitochondrial ribosomal protein S16.	0.941
LOC100697135	mrps22	ENSONIP00000011679	ENSONIP00000018368	NDK domain-containing protein; Belongs to the NDK family.	Mitochondrial ribosomal protein S22.	0.948
LOC100697135	nme6	ENSONIP00000011679	ENSONIP00000068813	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase 6 isoform X1.	0.935
LOC100703020	ENSONIP00000016918	ENSONIP00000024381	ENSONIP00000016918	Nucleoside diphosphate kinase.	Adenylate kinase 9.	0.947
LOC100703020	LOC100697135	ENSONIP00000024381	ENSONIP00000011679	Nucleoside diphosphate kinase.	NDK domain-containing protein; Belongs to the NDK family.	0.962