Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
oxa1lOXA1L mitochondrial inner membrane protein. (494 aa)    
Predicted Functional Partners:
COX2
Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
   
 0.954
chchd1
Coiled-coil-helix-coiled-coil-helix domain containing 1.
    
 
 0.928
ATP6
ATP synthase subunit a.
  
 0.924
I3J4H2_ORENI
Uncharacterized protein.
  
 0.911
ndufab1
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.901
COX3
Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex.
   
 0.892
mrpl47
Mitochondrial ribosomal protein L47.
   
 
 0.881
Mtg1
Mitochondrial GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
   
  
 0.876
mrpl45
Mitochondrial ribosomal protein L45.
   
 
 0.873
mrpl2
Mitochondrial ribosomal protein L2.
   
 
 0.864
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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