STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sh2b1SH2B adaptor protein 1. (870 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.728
tyk2
Tyrosine-protein kinase.
    
 0.662
LOC100704264
Tyrosine-protein kinase.
    
 0.662
LOC100710044
Tyrosine-protein kinase.
    
 0.662
jak1
Tyrosine-protein kinase.
    
 0.662
LOC100692564
Tyrosine-protein kinase.
    
 0.662
LOC100697854
Tyrosine-protein kinase receptor.
    
 0.610
LOC100707581
Tyrosine-protein kinase receptor.
    
 0.610
LOC100711993
Tyrosine-protein kinase receptor.
    
 0.610
LOC100696191
Tyrosine-protein kinase receptor.
    
 0.610
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.