Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC100700355Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (475 aa)    
Predicted Functional Partners:
lef1
Lymphoid enhancer-binding factor 1.
    
 0.989
map3k7
Mitogen-activated protein kinase kinase kinase 7.
    
 0.947
ENSONIP00000058877
annotation not available
    
 0.947
tcf7
Transcription factor 7.
    
 0.946
tcf7l2
Transcription factor 7 like 2.
    
 0.946
foxo4
Forkhead box O4.
    
 0.887
foxo3
Forkhead box O3b.
    
 0.887
LOC100706939
Forkhead box O1 a.
    
 0.887
LOC100706370
Fork-head domain-containing protein.
    
 0.887
LOC100699299
Fork-head domain-containing protein.
    
 0.884
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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