STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cables1Cdk5 and Abl enzyme substrate 1. (542 aa)    
Predicted Functional Partners:
cdk5
Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.
    
 0.749
mib1
Mindbomb E3 ubiquitin protein ligase 1.
    
 
 0.714
ccna2
Cyclin A2; Belongs to the cyclin family.
     
 0.540
ccna1
Cyclin A1; Belongs to the cyclin family.
     
 0.540
LOC100692568
Cyclin E2; Belongs to the cyclin family.
    
 0.500
Ccne1
Cyclin E1; Belongs to the cyclin family.
    
 0.500
LOC102075526
Cyclin E2; Belongs to the cyclin family.
    
 0.500
CDK18
Cyclin dependent kinase 18; Belongs to the protein kinase superfamily.
   
 0.489
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.488
cdk6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.475
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.