Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gata6GATA binding protein 6. (534 aa)    
Predicted Functional Partners:
nkx2-5
NK2 homeobox 5.
   
 0.958
zfpm2
Zinc finger protein, FOG family member 2a.
    
 0.891
tbx20
T-box transcription factor 20.
   
 0.837
Nfatc4
Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1.
     
 0.814
sqstm1
Sequestosome 1.
    
  0.801
nfatc2
Nuclear factor of activated T cells 2a.
    
 0.801
SRF
Serum response factor.
    
 0.771
I3JWF9_ORENI
MADS-box domain-containing protein.
    
 0.771
LOC100702133
Forkhead box A3.
   
 0.750
LOC100709336
Forkhead box A2.
   
 0.749
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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