rab40c protein (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

rab40c

RAB40c, member RAS oncogene family. (279 aa)

Predicted Functional Partners:

eloc

0.785

rabggtb

0.770

LOC100703753

0.670

CUL5

0.670

I3JU14_ORENI

0.648

elob

0.648

LOC100690604

0.624

Rilpl2

0.606

coasy

0.606

mthfsd

0.585

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL5	I3JU14_ORENI	ENSONIP00000077732	ENSONIP00000012359	Cullin 5; Belongs to the cullin family.	Elongin B.	0.958
CUL5	elob	ENSONIP00000077732	ENSONIP00000014508	Cullin 5; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.958
CUL5	eloc	ENSONIP00000077732	ENSONIP00000051892	Cullin 5; Belongs to the cullin family.	Elongin C paralog a; Belongs to the SKP1 family.	0.994
CUL5	rab40c	ENSONIP00000077732	ENSONIP00000011889	Cullin 5; Belongs to the cullin family.	RAB40c, member RAS oncogene family.	0.670
I3JU14_ORENI	CUL5	ENSONIP00000012359	ENSONIP00000077732	Elongin B.	Cullin 5; Belongs to the cullin family.	0.958
I3JU14_ORENI	LOC100703753	ENSONIP00000012359	ENSONIP00000030318	Elongin B.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.958
I3JU14_ORENI	elob	ENSONIP00000012359	ENSONIP00000014508	Elongin B.	Ubiquitin-like domain-containing protein.	0.959
I3JU14_ORENI	eloc	ENSONIP00000012359	ENSONIP00000051892	Elongin B.	Elongin C paralog a; Belongs to the SKP1 family.	0.996
I3JU14_ORENI	rab40c	ENSONIP00000012359	ENSONIP00000011889	Elongin B.	RAB40c, member RAS oncogene family.	0.648
LOC100690604	rab40c	ENSONIP00000022480	ENSONIP00000011889	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	RAB40c, member RAS oncogene family.	0.624
LOC100690604	rabggtb	ENSONIP00000022480	ENSONIP00000023115	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.	0.987
LOC100703753	I3JU14_ORENI	ENSONIP00000030318	ENSONIP00000012359	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Elongin B.	0.958
LOC100703753	elob	ENSONIP00000030318	ENSONIP00000014508	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.958
LOC100703753	eloc	ENSONIP00000030318	ENSONIP00000051892	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Elongin C paralog a; Belongs to the SKP1 family.	0.994
LOC100703753	rab40c	ENSONIP00000030318	ENSONIP00000011889	CULLIN_2 domain-containing protein; Belongs to the cullin family.	RAB40c, member RAS oncogene family.	0.670
Rilpl2	rab40c	ENSONIP00000016725	ENSONIP00000011889	Rab interacting lysosomal protein-like 2.	RAB40c, member RAS oncogene family.	0.606
coasy	rab40c	ENSONIP00000020436	ENSONIP00000011889	CoA synthase.	RAB40c, member RAS oncogene family.	0.606
elob	CUL5	ENSONIP00000014508	ENSONIP00000077732	Ubiquitin-like domain-containing protein.	Cullin 5; Belongs to the cullin family.	0.958
elob	I3JU14_ORENI	ENSONIP00000014508	ENSONIP00000012359	Ubiquitin-like domain-containing protein.	Elongin B.	0.959
elob	LOC100703753	ENSONIP00000014508	ENSONIP00000030318	Ubiquitin-like domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.958