STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrwd1Leucine-rich repeats and WD repeat domain containing 1. (739 aa)    
Predicted Functional Partners:
I3KF05_ORENI
Uncharacterized protein.
    
 
 0.881
orc5
Origin recognition complex, subunit 5.
    
 
 0.853
orc3
Origin recognition complex, subunit 3.
    
 
 0.853
ticrr
Treslin_N domain-containing protein.
   
 
 0.625
Orc4
Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family.
    
 
 0.610
vwa5b2
Von Willebrand factor A domain containing 5B2.
      
 0.588
I3JQJ5_ORENI
Adhesion G protein-coupled receptor L3.1; Belongs to the G-protein coupled receptor 2 family.
    
   0.530
LOC100702950
Si:ch1073-186i23.1; Belongs to the G-protein coupled receptor 2 family.
    
   0.530
I3KHL0_ORENI
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
   0.530
adgrl2
Adhesion G protein-coupled receptor L2a; Belongs to the G-protein coupled receptor 2 family.
    
   0.530
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.