Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rassf4Ras association domain family member 4a. (317 aa)    
Predicted Functional Partners:
LOC100695319
Uncharacterized protein.
   
 0.858
stk3
Serine/threonine kinase 3 (STE20 homolog, yeast).
   
 0.858
eif5b
Eukaryotic translation initiation factor 5B.
    
 
 0.815
rassf5
Ras association domain family member 5.
    
 
 0.779
sav1
Salvador family WW domain containing protein 1.
    
 
 0.590
emb
Embigin.
   
   0.579
LOC102081604
Transmembrane protein 119b.
      
 0.526
ankdd1a
Ankyrin repeat and death domain containing 1A.
     
 0.525
sowahd
Sosondowah ankyrin repeat domain family d.
     
 0.525
LOC100704366
Transmembrane protein 151A.
      
 0.521
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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