Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dhx30DEAH (Asp-Glu-Ala-His) box helicase 30. (1156 aa)    
Predicted Functional Partners:
ENSONIP00000000682
Intersectin 2a.
   
 0.786
I3KKD0_ORENI
Intersectin 2b.
   
 0.786
Helz2
Uncharacterized protein.
   
 0.746
itsn1
Intersectin 1 (SH3 domain protein).
    
  0.738
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.699
grsf1
G-rich RNA sequence binding factor 1.
    
 
 0.683
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
   
 0.673
dhx58
Probable ATP-dependent RNA helicase DHX58.
   
 
 0.660
rps2
Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
   
  0.652
mtrex
Mtr4 exosome RNA helicase.
   
 0.649
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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