Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
irf4Interferon regulatory factor 4a. (460 aa)    
Predicted Functional Partners:
il10
Interleukin 10.
   
 
 0.727
spi1
Spi-1 proto-oncogene b.
   
 
 0.702
LOC100704899
Interferon regulatory factor.
  
0.685
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.663
ppp2r1b
Protein phosphatase 2, regulatory subunit A, beta b.
    
  0.535
batf
Basic leucine zipper transcription factor, ATF-like.
   
 
 0.530
suox
Sulfite oxidase.
     
  0.503
Aicda
Activation-induced cytidine deaminase.
      
 0.499
LOC100704522
Zinc finger protein 366.
    
 0.474
bcl6
BCL6A transcription repressor a.
    
 0.469
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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