Plau protein (Oreochromis niloticus) - STRING interaction network

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Plau

Plasminogen activator, urokinase a; Belongs to the peptidase S1 family. (391 aa)

Predicted Functional Partners:

serpine1

0.974

serpine2

0.943

serping1

0.834

LOC100702671

0.751

LOC100702940

0.751

LOC100697028

0.690

I3K5Y3_ORENI

0.690

pdgfc

0.667

I3KUM9_ORENI

0.659

pdgfd

0.615

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3K5Y3_ORENI	LOC100702671	ENSONIP00000033897	ENSONIP00000045810	SERPIN domain-containing protein; Belongs to the serpin family.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.900
I3K5Y3_ORENI	LOC100702940	ENSONIP00000033897	ENSONIP00000069733	SERPIN domain-containing protein; Belongs to the serpin family.	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.900
I3K5Y3_ORENI	Plau	ENSONIP00000033897	ENSONIP00000012110	SERPIN domain-containing protein; Belongs to the serpin family.	Plasminogen activator, urokinase a; Belongs to the peptidase S1 family.	0.690
I3K5Y3_ORENI	serpine2	ENSONIP00000033897	ENSONIP00000013534	SERPIN domain-containing protein; Belongs to the serpin family.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.	0.862
I3K5Y3_ORENI	serping1	ENSONIP00000033897	ENSONIP00000018403	SERPIN domain-containing protein; Belongs to the serpin family.	Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family.	0.869
I3KUM9_ORENI	LOC100702671	ENSONIP00000032624	ENSONIP00000045810	Protein S100; Belongs to the S-100 family.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.708
I3KUM9_ORENI	LOC100702940	ENSONIP00000032624	ENSONIP00000069733	Protein S100; Belongs to the S-100 family.	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.708
I3KUM9_ORENI	Plau	ENSONIP00000032624	ENSONIP00000012110	Protein S100; Belongs to the S-100 family.	Plasminogen activator, urokinase a; Belongs to the peptidase S1 family.	0.659
I3KUM9_ORENI	serping1	ENSONIP00000032624	ENSONIP00000018403	Protein S100; Belongs to the S-100 family.	Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family.	0.578
LOC100697028	LOC100702671	ENSONIP00000005221	ENSONIP00000045810	SERPIN domain-containing protein; Belongs to the serpin family.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.900
LOC100697028	LOC100702940	ENSONIP00000005221	ENSONIP00000069733	SERPIN domain-containing protein; Belongs to the serpin family.	Plasminogen; Belongs to the peptidase S1 family. Plasminogen subfamily.	0.900
LOC100697028	Plau	ENSONIP00000005221	ENSONIP00000012110	SERPIN domain-containing protein; Belongs to the serpin family.	Plasminogen activator, urokinase a; Belongs to the peptidase S1 family.	0.690
LOC100697028	serpine2	ENSONIP00000005221	ENSONIP00000013534	SERPIN domain-containing protein; Belongs to the serpin family.	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.	0.865
LOC100697028	serping1	ENSONIP00000005221	ENSONIP00000018403	SERPIN domain-containing protein; Belongs to the serpin family.	Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family.	0.866
LOC100702671	I3K5Y3_ORENI	ENSONIP00000045810	ENSONIP00000033897	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	SERPIN domain-containing protein; Belongs to the serpin family.	0.900
LOC100702671	I3KUM9_ORENI	ENSONIP00000045810	ENSONIP00000032624	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	Protein S100; Belongs to the S-100 family.	0.708
LOC100702671	LOC100697028	ENSONIP00000045810	ENSONIP00000005221	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	SERPIN domain-containing protein; Belongs to the serpin family.	0.900
LOC100702671	Plau	ENSONIP00000045810	ENSONIP00000012110	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	Plasminogen activator, urokinase a; Belongs to the peptidase S1 family.	0.751
LOC100702671	pdgfc	ENSONIP00000045810	ENSONIP00000001495	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family.	0.670
LOC100702671	pdgfd	ENSONIP00000045810	ENSONIP00000047132	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	Platelet derived growth factor d; Belongs to the PDGF/VEGF growth factor family.	0.648