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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (678 aa)    
Predicted Functional Partners:
tradd
Tnfrsf1a-associated via death domain.
   
 0.999
Fadd
Uncharacterized protein.
   
 0.998
LOC100694194
Receptor-interacting serine-threonine kinase 3.
  
 
0.997
LOC100702139
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.995
LOC109194206
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.994
I3KF49_ORENI
Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
   
 0.994
LOC100534578
Tumor necrosis factor b (TNF superfamily, member 2).
   
 0.991
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.989
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.989
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.989
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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